- Office Supplies, Equipment & Office Furniture Stores, Columbiana
- Oil & Gas Exploration & Development, Columbiana - Oil Field Exploration, Monitoring & Remediation
- Oil Change & Lubrication, Columbiana - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Columbiana - Oil Companies
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Columbiana
- Opticians, Columbiana
- Optometrists, Columbiana - Eye Doctors, Physicians & Surgeons (Optometry)
- Ornamental Greenhouses, Columbiana
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- Ornamental Metal Work, Columbiana - Steel, Iron, Bronze, etc
- Ornamental Nursery, Columbiana
- Ornamental Nursery Services, Columbiana
- Orthopedic Shoes, Columbiana
- Other Building Materials & Supplies, Columbiana
- Outdoor & Lawn & Garden Equipment Repair & Service, Columbiana
- Outdoor Furniture & Patio Furniture, Columbiana - Garden Furniture Stores
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