- Obstetricians & Gynecologists, Worthington - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Office & Meeting Equipment & Supplies Rental, Worthington
- Office Furniture & Equipment Rental & Leasing, Worthington
- Office Furniture & Equipment Repair & Refinish, Worthington
- Office Supplies, Equipment & Office Furniture Stores, Worthington
- Oil & Gas Exploration & Development, Worthington - Oil Field Exploration, Monitoring & Remediation
- Oil Change & Lubrication, Worthington - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Worthington - Oil Companies
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Worthington
- Opticians, Worthington
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- Optometrists, Worthington - Eye Doctors, Physicians & Surgeons (Optometry)
- Ornamental Nursery, Worthington
- Ornamental Nursery Services, Worthington
- Orthopedic & Prosthetic Appliances & Shoes, Worthington - Orthopedic Shoes
- Orthopedists, Worthington - Orthopedic Surgery Doctors, Physicians & Surgeons
- Osteoporosis Doctors, Worthington - Physicians & Surgeons
- Other Building Materials & Supplies, Worthington
- Other Lodging, Worthington
- Oxygen & Respiratory Equipment & Supplies, Worthington - Oxygen Concentrator, Tank, Machine, etc
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